The Dhaka National Medical College inherits her glorious predecessor the Dhaka National Medical Institute, which was established in 1925 as a part of Non-cooperation movement of the Indian Sub-continent against the British colonial rule, organized jointly by the Indian National Congress and the Indian Muslim Leage under the Leadership of Mahatma Gandhi, Mawlana Muhammad Ali and Mawlana Sawkat Ali.Along with other programs the Non-cooperation movement urged upon the peoples of the sub-continent to boycott educational institutions established and administered by British Govt. and to establish National Schools, Colleges and Institutes for modern scientific education by the local people themselves. Accordingly two Medical School were established in the Bengal Province for producing National Doctors of modern medicine. One such Medical School was at Calcutta, named Calcutta National Medical Institute and the other at Dhaka, named Dhaka National Medical Institute.In 1971, during the Liberation war of Bangladesh the Dhaka National Medical Institute Hospital was a safe shelter for the Freedom Fighters. Just after the liberation of Bangladesh in 1972 the hospital condition was on the verge of collapse due to financial crisis and absence of any Administrative Body as the previous Governing Body and the Trustee Board of the Institute were almost absent.Father of the Nation of Bangladesh, Bangabandhu Sheikh Mujibur Rahman took initiative by himself to rescue the Dhaka National Medical Institute Hospital and granted a Taka of Thirty five lacs immediately for running the hospital and an Adhoc Governing Body was formed for the Institute hospital under the chairmanship of Mr. M. Sirajul Islam MLA for the smooth administration and development of the hospital. Mr. M. Sirajul Islam took active initiative to allocate a donation fo taka twenty five lacs from Bangladesh Assistance Society of India.